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Timestamps ⏱

0:00 – Intro
0:29 – Metabolic Reboot vs Optimization
1:30 – Fasting Insulin, HOMA-IR & Visceral Fat – Who Needs a Reset
3:44 – The Reboot Protocol – Up to 3 Days Every 3 Weeks
4:22 – Willpower vs Medical Assistance When Fasting
5:36 – Statins vs Lipid Management – Focus on Outcomes
6:58 – Is a 3-Day Fast Safe If You’re Metabolically Unhealthy?
7:18 – $20 off Your First 3 Thrive Market Orders + Free Gift
8:27 – The Carb-to-Fat Gap, Shakiness & Food Noise
11:10 – Why Glucose Stays High During a Multi-Day Fast
12:45 – The Liver – Your Metabolic Supercomputer
15:27 – Gluconeogenesis Myth – You’re Not Just Burning Muscle
18:21 – Metabolic Triage – Bigger Problems Need a Bigger Hammer
20:21 – Calories In, Calories Out – Why It Works but Plateaus
23:39 – Fasting + Lowering Insulin – The Best Strategy
26:20 – Retatrutide & the Insulin-Glucagon Dance
28:10 – Intermittent Fasting vs True Fasting
31:12 – Retatrutide’s Triple Agonist & the 4mg Glucagon Threshold
34:45 – Can Glucagon Rise Naturally During a Fast?
36:03 – Why Ketones Are the Best Fasting Biomarker
37:59 – Starvation vs Fasting Physiology – Cortisol vs AMPK
39:29 – Calories Out & Fuel Utilization – Anchor Fasting to the Gym
42:18 – Mitochondria, Urolithin A & Fasting
46:55 – AMPK vs mTOR – Who’s Leading the Dance
48:24 – Fine-Tuning Dials – Urolithin A, Dihydroberberine & Metformin
50:22 – Why You Should Lose Visceral Fat Fast
53:29 – Diabetes Mortality Risk & Why Time-Restricted Eating Isn’t Enough
55:25 – Where to Find More of Dr. Schoeff